Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Composition and architecture of the Schizosaccharomyces pombe Rad18 (Smc5-6) complex.

Molecular and cellular biology - 1 Jan 2005

Sergeant John, Taylor Elaine, Palecek Jan, Fousteri Maria, Andrews Emily A, Sweeney Sara, Shinagawa Hideo, Watts Felicity Z, Lehmann Alan R

Abstract excerpt

The rad18 gene of Schizosaccharomyces pombe is an essential gene that is involved in several different DNA repair processes. Rad18 (Smc6) is a member of the structural maintenance of chromosomes (SMC) family and, together with its SMC partner Spr18 (Smc5), forms the core of a high-molecular-weight complex. We show here that both S. pombe and human Smc5 and -6 interact through their hinge domains and that four...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immunoprecipitation
Share to Chromosomal Proteins, Non-Histone

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dose-Response Relationship, Radiation

Share to Glycine

Share to Mass Spectrometry

Share to Schizosaccharomyces

Share to Schizosaccharomyces pombe Proteins

Share to Two-Hybrid System Techniques

Source

Open in PubMed Open full text

Identifiers

PMID: 15601840
DOI: 10.1128/MCB.25.1.172-184.2005
PMCID: PMC538765

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Composition and architecture of the Schizosaccharomyces pombe Rad18 (Smc5-6) complex.PMID 15601840Read ↗

A novel SMC protein complex in Schizosaccharomyces pombe contains the Rad18 DNA repair protein.Semantic proximity Read ↗

Nse2, a component of the Smc5-6 complex, is a SUMO ligase required for the response to DNA damage.Semantic proximity Read ↗

Identification of a novel non-structural maintenance of chromosomes (SMC) component of the SMC5-SMC6 complex involved in DNA repair.Semantic proximity Read ↗

Specialized interfaces of Smc5/6 control hinge stability and DNA association.Semantic proximity Read ↗

Molecular Insights into the Architecture of the Human SMC5/6 Complex.Semantic proximity Read ↗

Structure of Mre11-Nbs1 complex yields insights into ataxia-telangiectasia-like disease mutations and DNA damage signaling.Semantic proximity Read ↗

Novel essential DNA repair proteins Nse1 and Nse2 are subunits of the fission yeast Smc5-Smc6 complex.Semantic proximity Read ↗

Schizosaccharomyces pombe centromere protein Mis19 links Mis16 and Mis18 to recruit CENP-A through interacting with NMD factors and the SWI/SNF complex.Semantic proximity Read ↗

Coordination of DNA damage responses via the Smc5/Smc6 complex.Semantic proximity Read ↗

Structure Basis for Shaping the Nse4 Protein by the Nse1 and Nse3 Dimer within the Smc5/6 Complex.Semantic proximity Read ↗

Crucial role of the NSE1 RING domain in Smc5/6 stability and FANCM-independent fork progression.Semantic proximity Read ↗

Allelic Analysis of smc-6 Reveals Domain-Specific Roles in DNA Repair in Caenorhabditis elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.