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ERCC2 genotypes and a corresponding haplotype are linked with breast cancer risk in a German population.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2004

Justenhoven Christina, Hamann Ute, Pesch Beate, Harth Volker, Rabstein Sylvia, Baisch Christian, Vollmert Caren, Illig Thomas, Ko Yon-Dschun, Brüning Thomas, Brauch Hiltrud

Abstract excerpt

The polygenic concept of breast cancer susceptibility calls for the identification of genetic variants that contribute to breast cancer risk. Reduced DNA repair proficiencies in women with breast cancer pointed to a possible role of DNA repair enzymes in the risk to develop the disease. The nucleotide excision repair enzyme encoded by the excision repair cross-complementing group 2 gene ERCC2 (formerly XPD) known...

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PMID: 15598761

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ERCC2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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