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Article

Polygenic model of DNA repair genetic polymorphisms in human breast cancer risk.

Carcinogenesis - 1 Nov 2008

Smith Tasha R, Levine Edward A, Freimanis Rita I, Akman Steven A, Allen Glenn O, Hoang Kimberly N, Liu-Mares Wen, Hu Jennifer J

Abstract excerpt

Genetic variations in DNA repair may impact repair functions, DNA damage and breast cancer risk. Using data/samples collected from the first 752 Caucasians and 141 African-Americans in an ongoing case-control study, we examined the association between breast cancer risk and 18 non-synonymous sing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18701435
DOI: 10.1093/carcin/bgn193
PMCID: PMC2722862

Genes

ERCC4
MLH1
ERCC2
ERCC5
MSH3
MSH6
POLD1
XPC
XRCC1
XRCC3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18701435-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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