Article
Single-nucleotide polymorphisms in DNA repair genes and association with breast cancer risk in the web study.
Carcinogenesis - 1 Aug 2011
Roberts Michelle R, Shields Peter G, Ambrosone Christine B, Nie Jing, Marian Catalin, Krishnan Shiva S, Goerlitz David S, Modali Ramakrishna, Seddon Michael, Lehman Teresa, Amend Kandace L, Trevisan Maurizio, Edge Stephen B, Freudenheim Jo L
Abstract excerpt
Base excision repair (BER) and nucleotide excision repair (NER) pathways repair damaged DNA, and polymorphisms in these genes might affect breast cancer susceptibility. We evaluated associations between seven single-nucleotide polymorphisms in four DNA repair genes (ERCC4 rs1799801, XPC rs2227998, rs2228001, rs2228000, OGG1 rs1052133 and XRCC1 and ) and breast cancer risk, examining modification by...
