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Article

DNA repair gene ERCC2 polymorphisms and associations with breast and ovarian cancer risk.

Molecular cancer - 2 May 2008

Bernard-Gallon Dominique, Bosviel Rémy, Delort Laetitia, Fontana Luc, Chamoux Alain, Rabiau Nadège, Kwiatkowski Fabrice, Chalabi Nasséra, Satih Samir, Bignon Yves-Jean

Abstract excerpt

Breast and ovarian cancers increased in the last decades. Except rare cases with a genetic predisposition and high penetrance, these pathologies are viewed as a polygenic disease. In this concept, association studies look for genetic variations such as polymorphisms in low penetrance genes, i.e. genes in interaction with environmental factors. DNA repair systems that protect the genome from deleterious endogenous...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18454848
DOI: 10.1186/1476-4598-7-36
PMCID: PMC2394522

Genes

ERCC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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