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Article

Mice lacking IGF-I and LIF have motoneuron deficits in brain stem nuclei.

Neuroreport - 22 Dec 2004

Vicario-Abejón Carlos, Fernández-Moreno Carmen, Pichel José G, de Pablo Flora

Abstract excerpt

We analyzed the neural embryonic phenotype of single and double-mutant mice for insulin-like growth factor-I (IGF-I) and leukemia inhibitory factor (LIF). The anatomical structure of the hippocampus, the cerebellum, and the olfactory epithelium, regions showing expression of both factors and their receptors, appeared largely normal in all mutant mice. In the fimbria and the spinal cord, similar patterns of glial...

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Source

Identifiers

PMID: 15597051

Genes

LIF
GFAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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