Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ebf1 controls early cell differentiation in the embryonic striatum.

Development (Cambridge, England) - 1 Dec 1999

Garel S, Marín F, Grosschedl R, Charnay P

Abstract excerpt

Ebf1/Olf-1 belongs to a small multigene family encoding closely related helix-loop-helix transcription factors, which have been proposed to play a role in neuronal differentiation. Here we show that Ebf1 controls cell differentiation in the murine embryonic striatum, where it is the only gene of the family to be expressed. Ebf1 targeted disruption affects postmitotic cells that leave the subventricular zone (SVZ)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Atrophy
Share to Cell Compartmentation
Share to Corpus Striatum

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fetal Proteins

Share to Nerve Fibers

Share to Receptor Protein-Tyrosine Kinases

Share to Receptors, Retinoic Acid

Share to Retinoic Acid Receptor alpha

Source

Identifiers

PMID: 10556054
DOI: 10.1242/dev.126.23.5285

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ebf1 controls early cell differentiation in the embryonic striatum.PMID 10556054Read ↗

Integrative genomic analysis of early neurogenesis reveals a temporal genetic program for differentiation and specification of preplate and Cajal-Retzius neuronsSemantic proximity Read ↗

Family of Ebf/Olf-1-related genes potentially involved in neuronal differentiation and regional specification in the central nervous system.Semantic proximity Read ↗

Cell‐context specific role of the E2F/Rb pathway in development and diseaseSemantic proximity Read ↗

Cell cycle deregulation and loss of stem cell phenotype in the subventricular zone of TGF-beta adaptor elf-/- mouse brain.Semantic proximity Read ↗

Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres.Semantic proximity Read ↗

Embryonic cortical neural stem cells migrate ventrally and persist as postnatal striatal stem cells.Semantic proximity Read ↗

Unraveling Lineage Roadmaps and Cell Fate Determinants to Postnatal Neural Stem Cells and Ependymal cells in the Developing Ventricular ZoneSemantic proximity Read ↗

Two parallel lineage-committed progenitors contribute to the developing brainSemantic proximity Read ↗

Combined single-cell RNA-seq profiling and enhancer editing reveals critical spatiotemporal controls over thalamic nuclei formation in the murine embryoSemantic proximity Read ↗

Mutations of the homeobox genes Dlx-1 and Dlx-2 disrupt the striatal subventricular zone and differentiation of late born striatal neurons.Semantic proximity Read ↗

Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells.Semantic proximity Read ↗

Expression of the bHLH transcription factor Tcf12 (ME1) gene is linked to the expansion of precursor cell populations during neurogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.