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Article

Fkh5-deficient mice show dysgenesis in the caudal midbrain and hypothalamic mammillary body.

Development (Cambridge, England) - 1 Nov 1997

Wehr R, Mansouri A, de Maeyer T, Gruss P

Abstract excerpt

The murine winged helix gene Fkh5 is specifically expressed in the developing central nervous system (CNS). Early embryonic Fkh5 expression is restricted to the mammiliary body region of the caudal hypothalamus, midbrain, hindbrain and spinal cord. Postnatally, signals persist in specific nuclei of the mammillary body and in the midbrain. We generated Fkh5 deficient mice by homologous recombination to assess its...

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PMID: 9409663
DOI: 10.1242/dev.124.22.4447

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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