Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Fkh5-deficient mice show dysgenesis in the caudal midbrain and hypothalamic mammillary body.

Development (Cambridge, England) - 1 Nov 1997

Wehr R, Mansouri A, de Maeyer T, Gruss P

Abstract excerpt

The murine winged helix gene Fkh5 is specifically expressed in the developing central nervous system (CNS). Early embryonic Fkh5 expression is restricted to the mammiliary body region of the caudal hypothalamus, midbrain, hindbrain and spinal cord. Postnatally, signals persist in specific nuclei...

Topics

Join the communities discussing this publication.

Phenotype
Genotype
Mice
DNA-Binding Proteins
Transcription Factors
Mice, Inbred C57BL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Expression Regulation, Developmental

Source

Identifiers

PMID: 9409663
DOI: 10.1242/dev.124.22.4447

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-9409663-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fkh5-deficient mice show dysgenesis in the caudal midbrain and hypothalamic mammillary body.PMID 9409663Read ↗

FKBP8 is a negative regulator of mouse sonic hedgehog signaling in neural tissues.Semantic proximity Read ↗

The winged helix gene, Mf3, is required for normal development of the diencephalon and midbrain, postnatal growth and the milk-ejection reflex.Semantic proximity Read ↗

Cooperation of Pax2 and Pax5 in midbrain and cerebellum development.Semantic proximity Read ↗

Loss of the serine/threonine kinase fused results in postnatal growth defects and lethality due to progressive hydrocephalus.Semantic proximity Read ↗

A genomic atlas of mouse hypothalamic development.Semantic proximity Read ↗

The ciliary Frizzled-like receptor Tmem67 regulates canonical Wnt/β-catenin signalling in the developing cerebellum via Hoxb5Semantic proximity Read ↗

Embryonic phenotype of Unc5h3 mutant mice suggests chemorepulsion during the formation of the rostral cerebellar boundary.Semantic proximity Read ↗

Conserved biological function between Pax-2 and Pax-5 in midbrain and cerebellum development: evidence from targeted mutations.Semantic proximity Read ↗

Fgf8b-containing spliceforms, but not Fgf8a, are essential for Fgf8 function during development of the midbrain and cerebellum.Semantic proximity Read ↗

Mouse Fkbp8 activity is required to inhibit cell death and establish dorso-ventral patterning in the posterior neural tube.Semantic proximity Read ↗

Loss of Dynein Axonemal Heavy Chain 5 Causes Cortical Development Disorders and CSF Flow StagnationSemantic proximity Read ↗

Neural crest-specific removal of Zfhx1b in mouse leads to a wide range of neurocristopathies reminiscent of Mowat-Wilson syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.