Analysis of neuronal and glial phenotypes in brains of mice deficient in leukemia inhibitory factor.

doi:10.1002/(sici)1097-4695(19980915)36:4<509::aid-neu5>3.0.co;2-#

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Article

Analysis of neuronal and glial phenotypes in brains of mice deficient in leukemia inhibitory factor.

Journal of neurobiology - 15 Sept 1998

Bugga L, Gadient R A, Kwan K, Stewart C L, Patterson P H

Abstract excerpt

Leukemia inhibitory factor (LIF) can regulate the survival and differentiation of certain neurons and glial cells in culture. To determine the role of this cytokine in the central nervous system in vivo, we examined the brains of young and adult mice in which the LIF gene was disrupted. Immunohis...

Topics

Animals
Brain
Cell Count
Cell Differentiation
Female
Genotype
Glial Fibrillary Acidic Protein
Growth Inhibitors
Image Processing, Computer-Assisted
Immunoblotting
Immunohistochemistry
Interleukin-6

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Leukemia Inhibitory Factor

Lymphokines

Male

Mice

Mice, Inbred C57BL

Mice, Knockout

Source

Open in PubMed

Identifiers

PMID: 9740023
DOI: 10.1002/(sici)1097-4695(19980915)36:4<509::aid-neu5>3.0.co;2-#

Genes

LIF
GFAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9740023-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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