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Article

Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres.

Neuron - 1 Jun 1995

Xuan S, Baptista C A, Balas G, Tao W, Soares V C, Lai E

Abstract excerpt

We generated mice with a null mutation of the forebrain-restricted transcription factor BF-1 to examine its function in brain development. Heterozygous animals have an apparently normal phenotype. Homozygous null BF-1 mutants die at birth and have a dramatic reduction in the size of the cerebral hemispheres. The development of the ventral telencephalon is more severely affected than that of the dorsal...

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Identifiers

PMID: 7605629
DOI: 10.1016/0896-6273(95)90262-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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