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Article

The transcription factor Nfix is essential for normal brain development.

BMC developmental biology - 13 May 2008

Campbell Christine E, Piper Michael, Plachez Céline, Yeh Yu-Ting, Baizer Joan S, Osinski Jason M, Litwack E David, Richards Linda J, Gronostajski Richard M

Abstract excerpt

BACKGROUND: The Nuclear Factor I (NFI) multi-gene family encodes site-specific transcription factors essential for the development of a number of organ systems. We showed previously that Nfia-deficient mice exhibit agenesis of the corpus callosum and other forebrain defects; Nfib-deficient mice have defects in lung maturation and show callosal agenesis and forebrain defects resembling those seen in Nfia-deficient...

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Identifiers

PMID: 18477394
DOI: 10.1186/1471-213X-8-52
PMCID: PMC2414869

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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