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Article

Haplotype-based analysis of alpha 2A, 2B, and 2C adrenergic receptor genes captures information on common functional loci at each gene.

Journal of human genetics - 1 Jan 2005

Belfer Inna, Buzas Beata, Hipp Heather, Phillips Gabriel, Taubman Julie, Lorincz Ilona, Evans Catherine, Lipsky Robert H, Enoch Mary-Anne, Max Mitchell B, Goldman David

Abstract excerpt

The alpha 2-adrenergic receptors (alpha2-AR) mediate physiological effects of epinephrine and norepinephrine. Three genes encode alpha2-AR subtypes carrying common functional polymorphisms (ADRA2A Asn251Lys, ADRA2B Ins/Del301-303 and ADRA2C Ins/Del322-325). We genotyped these functional markers plus a panel of single nucleotide polymorphisms evenly spaced over the gene regions to identify gene haplotype block...

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PMID: 15592690
DOI: 10.1007/s10038-004-0211-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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