Article
Haplotype structure of the beta adrenergic receptor genes in US Caucasians and African Americans.
European journal of human genetics : EJHG - 1 Mar 2005
Belfer Inna, Buzas Beata, Evans Catherine, Hipp Heather, Phillips Gabriel, Taubman Julie, Lorincz Ilona, Lipsky Robert H, Enoch Mary-Anne, Max Mitchell B, Goldman David
Abstract excerpt
The beta-adrenergic receptors (beta-AR) are G protein-coupled receptors activated by epinephrine and norepinephrine and are involved in a variety of their physiological functions. Previously, three beta-AR genes (ADRB1, ADRB2 and ADRB3) were resequenced, identifying polymorphisms that were used in genetic association studies of cardiovascular and metabolic disorders. These studies have produced intriguing but...
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