Article
Sequence, haplotype, and association analysis of ADRbeta2 in a multiethnic asthma case-control study.
American journal of respiratory and critical care medicine - 15 Nov 2006
Hawkins Gregory A, Tantisira Kelan, Meyers Deborah A, Ampleford Elizabeth J, Moore Wendy C, Klanderman Barbara, Liggett Stephen B, Peters Stephen P, Weiss Scott T, Bleecker Eugene R
Abstract excerpt
RATIONALE: The comprehensive evaluation of gene variation, haplotype structure, and linkage disequilibrium is important in understanding the function of beta2-adrenergic receptor gene (ADRbeta2) on disease susceptibility, pulmonary function, and therapeutic responses in different ethnic groups with asthma. OBJECTIVES: To identify ADRbeta2 polymorphisms and haplotype structure in white and African American...
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