Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Common ADRB2 haplotypes derived from 26 polymorphic sites direct beta2-adrenergic receptor expression and regulation phenotypes.

PloS one - 29 Jul 2010

Panebra Alfredo, Wang Wayne C, Malone Molly M, Pitter Demar R G, Weiss Scott T, Hawkins Gregory A, Liggett Stephen B

Abstract excerpt

BACKGROUND: The beta2-adrenergic receptor (beta2AR) is expressed on numerous cell-types including airway smooth muscle cells and cardiomyocytes. Drugs (agonists or antagonists) acting at these receptors for treatment of asthma, chronic obstructive pulmonary disease, and heart failure show substan...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to 5' Untranslated Regions
Share to Blotting, Western

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chlorocebus aethiops

Share to COS Cells

Share to Promoter Regions, Genetic

Share to Receptors, Adrenergic, beta-2

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 20686604
DOI: 10.1371/journal.pone.0011819
PMCID: PMC2912278

Genes

ADRB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20686604-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Common ADRB2 haplotypes derived from 26 polymorphic sites direct beta2-adrenergic receptor expression and regulation phenotypes.PMID 20686604Read ↗

Complex promoter and coding region beta 2-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness.Semantic proximity Read ↗

Complex haplotypes derived from noncoding polymorphisms of the intronless alpha2A-adrenergic gene diversify receptor expression.Semantic proximity Read ↗

Haplotype-based analysis of alpha 2A, 2B, and 2C adrenergic receptor genes captures information on common functional loci at each gene.Semantic proximity Read ↗

beta(2)-adrenergic receptor promoter haplotype influences spirometric response during an acute asthma exacerbation.Semantic proximity Read ↗

Beta 2 adrenergic receptor 5' haplotypes influence promoter activity.Semantic proximity Read ↗

Molecular-based haplotype analysis of the beta 2-adrenergic receptor gene (ADRB2) in Japanese asthmatic and non-asthmatic subjects.Semantic proximity Read ↗

Genetic variation within the beta1-adrenergic receptor gene results in haplotype-specific expression phenotypes.Semantic proximity Read ↗

Genetic variation of the beta(2)-adrenoceptor: its functional and clinical importance in bronchial asthma.Semantic proximity Read ↗

Sequence, haplotype, and association analysis of ADRbeta2 in a multiethnic asthma case-control study.Semantic proximity Read ↗

Variations in the alpha2A-adrenergic receptor gene and their functional effects.Semantic proximity Read ↗

Haplotype structure of the beta adrenergic receptor genes in US Caucasians and African Americans.Semantic proximity Read ↗

Interactive effects of common beta2-adrenoceptor haplotypes and age on susceptibility to hypertension and receptor function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.