Haplotype block and superblock structures of the alpha1-adrenergic receptor genes reveal echoes from the chromosomal past.

doi:10.1007/s00438-004-1074-9

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Article

Haplotype block and superblock structures of the alpha1-adrenergic receptor genes reveal echoes from the chromosomal past.

Molecular genetics and genomics : MGG - 1 Dec 2004

Buzas B, Belfer I, Hipp H, Lorincz I, Evans C, Phillips G, Taubman J, Max M B, Goldman D

Abstract excerpt

A significant proportion of the human genome is contained within haplotype blocks across which pairwise linkage disequilibrium (LD) is very high. However, LD is also often high between markers at more remote distances, and within different haplotype blocks. Here, we evaluate the origins of haplotype block structure in the three genes for alpha1 adrenergic receptors (alpha1-AR) in the human genome ( ADRA1A, ADRA1B...

Topics

Black or African American
Genome, Human
Genotype
Haplotypes
Humans
Linkage Disequilibrium
Polymorphism, Single Nucleotide
Receptors, Adrenergic, alpha-1
United States
White People

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Open in PubMed

Identifiers

PMID: 15503142
DOI: 10.1007/s00438-004-1074-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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