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Article

Novel function of the flap endonuclease 1 complex in processing stalled DNA replication forks.

EMBO reports - 1 Jan 2005

Zheng Li, Zhou Mian, Chai Qing, Parrish Jay, Xue Ding, Patrick Steve M, Turchi John J, Yannone Steven M, Chen David, Shen Binghui

Abstract excerpt

Restarting stalled replication forks partly depends on the break-induced recombination pathway, in which a DNA double-stranded break (DSB) is created on the stalled replication fork to initiate the downstream recombination cascades. Single-stranded DNA gaps accumulating on stalled replication forks are potential targets for endonucleases to generate DSBs. However, it is unclear how this process is executed and...

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Identifiers

PMID: 15592449
DOI: 10.1038/sj.embor.7400313
PMCID: PMC1299223

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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