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Article

Role of Candida albicans transcription factor Upc2p in drug resistance and sterol metabolism.

Eukaryotic cell - 1 Dec 2004

Silver Peter M, Oliver Brian G, White Theodore C

Abstract excerpt

In Candida albicans, drug resistance to clinically important antifungal drugs may be regulated through the action of transcription factors in a manner that may or may not be similar to regulation in Saccharomyces cerevisiae. A search of the C. albicans genome identified a single homolog of the S. cerevisiae transcription factor genes UPC2 (ScUPC2) and ECM22 (ScECM22) that have been associated with regulation of...

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Identifiers

PMID: 15590814
DOI: 10.1128/EC.3.6.1391-1397.2004
PMCID: PMC539032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Role of Candida albicans transcription factor Upc2p in drug resistance and sterol metabolism.PMID 15590814Read ↗

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cis-Acting elements within the Candida albicans ERG11 promoter mediate the azole response through transcription factor Upc2p.Semantic proximity Read ↗

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