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Article

Upc2p-associated differential protein expression in Candida albicans.

Proteomics - 1 Oct 2009

Hoehamer Christopher F, Cummings Edwin D, Hilliard George M, Morschhäuser Joachim, David Rogers Phillip

Abstract excerpt

The gain-of-function mutation G648D in UPC2 causes ERG11 up-regulation and increased fluconazole resistance in Candida albicans. In this study, we performed 2-DE and PMF to identify proteomic alterations in an ERG11-overexpressing fluconazole-resistant C. albicans clinical isolate compared with its fluconazole-susceptible parent strain. We identified 23 differentially expressed proteins, and among them, seven...

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Source

Identifiers

PMID: 19750515
DOI: 10.1002/pmic.200900176

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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