Article
Receptor revision and atypical mutational characteristics in clonally expanded B cells from the cerebrospinal fluid of recently diagnosed multiple sclerosis patients.
Journal of neuroimmunology - 1 Jan 2005
Monson Nancy L, Brezinschek Hans-Peter, Brezinschek Ruth I, Mobley Angela, Vaughan Gwen K, Frohman Elliot M, Racke Michael K, Lipsky Peter E
Abstract excerpt
PURPOSE: To determine whether cerebrospinal fluid (CSF) B cells exhibit clonal expansion in patients recently diagnosed with multiple sclerosis (MS). CSF B cell clonal expansion was detected early in the disease process. Evidence of receptor revision was present in at least one MS patient who had...
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