Article
Oligoclonal B lymphocyte expansion in the synovium of a patient with Behçet's disease.
Arthritis and rheumatism - 1 Jul 2001
Suh C H, Park Y B, Song J, Lee C H, Lee S K
Abstract excerpt
OBJECTIVE: Plasma cell infiltration is observed in recurrent arthritis associated with Behçet's disease (BD). The immune mechanism underlying B lymphocyte proliferation in the synovium is unclear. One hypothesis involves nonspecific polyclonal activation and another involves antigen-driven activation. The present study was undertaken to test both hypotheses and identify immunoglobulin genes that are clonally...
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