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Article

Multiple sclerosis: T-cell receptor expression in distinct brain regions.

Brain : a journal of neurology - 1 Nov 2007

Junker Andreas, Ivanidze Jana, Malotka Joachim, Eiglmeier Ingrid, Lassmann Hans, Wekerle Hartmut, Meinl Edgar, Hohlfeld Reinhard, Dornmair Klaus

Abstract excerpt

Multiple sclerosis (MS) is an inflammatory demyelinating disease where T cells attack the brain and the spinal cord. It is known that often particular T-cell clones are expanded in the target tissue, but it is still unknown, whether identical T-cell clones are present at distinct anatomical sites, or whether the T-cell spectrum is locally diverse. Therefore we compared the T-cell receptor (TCR) repertoire in...

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PMID: 17890278
DOI: 10.1093/brain/awm214

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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