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Article

Genetic association of low density lipoprotein receptor and Alzheimer's disease.

Neurobiology of aging - 1 Jan 2005

Gopalraj Rangaraj K, Zhu Haiyan, Kelly Jeremiah F, Mendiondo Marta, Pulliam Joseph F, Bennett David A, Estus Steven

Abstract excerpt

The low density lipoprotein receptor (LDLR) is an attractive candidate gene for genetic association with Alzheimer's disease (AD) because: (i) the LDLR is an apolipoprotein E (apoE) receptor, alleles of which have been associated with AD, (ii) LDLR resides at chromosome 19p13.3 within a region linked to AD, and (iii) LDLR modulates the homeostasis of cholesterol, which itself appears associated with AD....

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Source

Identifiers

PMID: 15585340
DOI: 10.1016/j.neurobiolaging.2004.09.001

Genes

LDLR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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