Article
Interleukin-23 receptor polymorphisms are associated with Alzheimer's disease in Han Chinese.
Journal of neuroimmunology - 15 Jun 2014
Liu Ying, Yu Jin-Tai, Zhang Wei, Zong Yu, Lu Rui-Chun, Zhou Jing, Tan Lan
Abstract excerpt
Inhibition of interleukin-23 (IL-23) signaling was reported to reduce AD pathology, and IL-23 receptor gene (IL23R) which encodes IL-23 receptor may represent a candidate susceptibility gene for AD. Here, we conducted a case-control association study to assess the effect of IL23R genetic polymorphisms on the risk of AD in a Northern Han Chinese population. Two tag functional single polymorphisms (SNPs),...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
