Article
Vitamin D receptor gene haplotype is associated with late-onset Alzheimer's disease.
The Tohoku journal of experimental medicine - 1 Nov 2012
Gezen-Ak Duygu, Dursun Erdinç, Bilgiç Basar, Hanağasi Hasmet, Ertan Turan, Gürvit Hakan, Emre Murat, Eker Engin, Ulutin Turgut, Uysal Omer, Yilmazer Selma
Abstract excerpt
Vitamin D(3) is a neurosteroid that mediates its effects via the vitamin D receptor (VDR). The VDR gene is located on chromosome 12q13 and consists of 9 exons. VDR contains the DNA-binding site encoded by exons 2 and 3 and the ligand-binding site encoded by exons 4 - 9. Our earlier study showed t...
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