Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigation of oxidized LDL-receptor 1 (OLR1) as the candidate gene for Alzheimer's disease on chromosome 12.

Human genetics - 1 Oct 2002

Luedecking-Zimmer Erin, DeKosky Steven T, Chen Qi, Barmada M Michael, Kamboh M Ilyas

Abstract excerpt

Late-onset Alzheimer's disease (AD) is a genetically heterogeneous neurodegenerative disorder. In addition to the apolipoprotein E (APOE) gene on chromosome 19, linkage studies suggest the existence of multiple susceptibility genes for late-onset AD. Genome-wide linkage and chromosome-12-specific linkage studies have identified a broad 50-cM pericentromeric region between 12p12 and 12q13 among non- APOE*4...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Apolipoprotein E4

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoproteins E

Share to Chromosomes, Human, Pair 12

Share to DNA Primers

Share to Linkage Disequilibrium

Share to Receptors, LDL

Share to Scavenger Receptors, Class E

Source

Identifiers

PMID: 12384789
DOI: 10.1007/s00439-002-0802-7

Genes

APOE
OLR1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigation of oxidized LDL-receptor 1 (OLR1) as the candidate gene for Alzheimer's disease on chromosome 12.PMID 12384789Read ↗

Fine mapping of the chromosome 12 late-onset Alzheimer disease locus: potential genetic and phenotypic heterogeneity.Semantic proximity Read ↗

Association of 3'-UTR polymorphisms of the oxidised LDL receptor 1 (OLR1) gene with Alzheimer's disease.Semantic proximity Read ↗

Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12.Semantic proximity Read ↗

The genetics of late-onset Alzheimer's disease.Semantic proximity Read ↗

Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12Semantic proximity Read ↗

Genome-wide linkage disequilibrium mapping of late-onset Alzheimer’s disease in FinlandSemantic proximity Read ↗

Further examination of the candidate genes in chromosome 12p13 locus for late-onset Alzheimer disease.Semantic proximity Read ↗

Association of the 3' UTR transcription factor LBP-1c/CP2/LSF polymorphism with late-onset Alzheimer's disease.Semantic proximity Read ↗

Functional interaction between APOE4 and LDL receptor isoforms in Alzheimer's disease.Semantic proximity Read ↗

Effect of heterogeneity on the chromosome 10 risk in late-onset Alzheimer disease.Semantic proximity Read ↗

Role of OLR1 and its regulating hsa-miR369-3p in Alzheimer's disease: genetics and expression analysis.Semantic proximity Read ↗

Vitamin D receptor and Alzheimer's disease: a genetic and functional study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.