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Article

DC-SIGN polymorphisms are associated to type 1 diabetes mellitus.

Immunobiology - 1 Nov 2014

da Silva Ronaldo Celerino, Cunha Tavares Nathália de Alencar, Moura Ronald, Coelho Antônio, Guimarães Rafael Lima, Araújo Jacqueline, Crovella Sergio, Brandão Lucas André Cavalcanti, Silva Jaqueline de Azevêdo

Abstract excerpt

Type I diabetes mellitus (T1DM) is an autoimmune disorder featured by raised glucoses levels. It has been hypothesised that raised glucose levels in T1DM might be recognised as PAMPs, leading to immune response by overloading the cell receptors for pathogens recognition. DC-SIGN is a transmembrane protein, present in dendritic cells (DC) and macrophages: it has an important role in inflammatory response and T...

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Share to Cell Adhesion Molecules
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25092567
DOI: 10.1016/j.imbio.2014.07.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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