Article
Impaired function of dendritic cells deficient in angiotensin II type 1 receptors.
The Journal of pharmacology and experimental therapeutics - 1 Sept 2010
Nahmod Karen, Gentilini Ciara, Vermeulen Monica, Uharek Lutz, Wang Yong, Zhang Jialin, Schultheiss Heinz-Peter, Geffner Jorge, Walther Thomas
Abstract excerpt
Dendritic cells (DC) are highly specialized antigen-presenting cells with a unique ability to activate resting T lymphocytes and initiate primary immune responses. Angiotensin II (AII) is involved in key events of the inflammatory response. Because our previous work implicated an effect of AII on differentiation and function of murine and human DC, we investigated the impact of AII type 1 receptor (AT(1))...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
