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Article

Reduced IFN-alpha secretion by blood dendritic cells in human diabetes.

Clinical immunology (Orlando, Fla.) - 1 Oct 2006

Summers Kelly L, Marleau Annette M, Mahon Jeffrey L, McManus Ruth, Hramiak Irene, Singh Bhagirath

Abstract excerpt

Characterization of dendritic cells (DC) in human diabetes has been restricted to monocyte-derived DC in type 1 diabetes, whose physiological relevance to endogenous DC is uncertain. Here, we provide the first report characterizing the phenotype and function of endogenous DC subsets in type 1 and type 2 diabetes. We show that DC subsets in each diabetic group exhibit normal properties concerning frequency and...

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Identifiers

PMID: 16859998
DOI: 10.1016/j.clim.2006.05.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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