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Article

Reduced CCR4, interleukin-13 and GATA-3 up-regulation in response to type 2 cytokines of cord blood T lymphocytes in infants at genetic risk of type 1 diabetes.

Immunology - 1 Jun 2007

Luopajärvi Kristiina, Skarsvik Susanne, Ilonen Jorma, Akerblom Hans K, Vaarala Outi

Abstract excerpt

Aberrancies in T-cell polarization including expression of chemokine receptors have been reported in human leucocyte antigen (HLA) class II associated autoimmune diseases, such as type 1 diabetes (T1D) and rheumatoid arthritis. We asked whether these aberrancies are present at birth in newborn infants carrying the HLA risk haplotypes for T1D. Sixty-seven cord blood (CB) samples from infants were screened for...

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Identifiers

PMID: 17244154
DOI: 10.1111/j.1365-2567.2007.02557.x
PMCID: PMC2265934

Genes

CCR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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