Article
A variant of beta fibrinogen is a genetic risk factor for coronary artery disease and myocardial infarction.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Apr 1996
Yu Q, Safavi F, Roberts R, Marian A J
Abstract excerpt
BACKGROUND: Coronary artery disease is a complex trait caused by a number of genetic and environmental factors. Genes involved in hemostasis and coagulation are excellent candidate genes for CAD and its thrombotic complications, i.e., myocardial infarction (MI) and unstable angina. METHODS: We de...
Topics
- Adult
- Aged
- Alleles
- Case-Control Studies
- Chromosomes, Human, Pair 4
- Coronary Disease
- Coronary Thrombosis
- Female
- Fibrinogen
- Gene Frequency
- Genotype
- Humans
- Male
- Middle Aged
- Myocardial Infarction
- Peptide Fragments
- Risk Factors