Article
A variant of beta fibrinogen is a genetic risk factor for coronary artery disease and myocardial infarction.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Apr 1996
Yu Q, Safavi F, Roberts R, Marian A J
Abstract excerpt
BACKGROUND: Coronary artery disease is a complex trait caused by a number of genetic and environmental factors. Genes involved in hemostasis and coagulation are excellent candidate genes for CAD and its thrombotic complications, i.e., myocardial infarction (MI) and unstable angina. METHODS: We determined the frequency of beta-fibrinogen genotypes in a homogenous patient population with CAD undergoing coronary...
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