Article
Fibrinogen beta variants confer protection against coronary artery disease in a Greek case-control study.
BMC medical genetics - 18 Feb 2010
Theodoraki Eirini V, Nikopensius Tiit, Suhorutsenko Julia, Peppes Vassileios, Fili Panagiota, Kolovou Genovefa, Papamikos Vassileios, Richter Dimitrios, Zakopoulos Nikolaos, Krjutskov Kaarel, Metspalu Andres, Dedoussis George V
Abstract excerpt
BACKGROUND: Although plasma fibrinogen levels are related to cardiovascular risk, data regarding the role of fibrinogen genetic variation in myocardial infarction (MI) or coronary artery disease (CAD) etiology remain inconsistent. The purpose of the present study was to investigate the effect of fibrinogen A (FGA), fibrinogen B (FGB) and fibrinogen G (FGG) gene SNPs and haplotypes on susceptibility to CAD in a...
Topics
- Acute Coronary Syndrome
- Aged
- Case-Control Studies
- Coronary Artery Disease
- Female
- Fibrinogen
- Gene Frequency
- Genes, Recessive
- Genetic Variation
- Greece