Article
Elevated plasma fibrinogen gamma' concentration is associated with myocardial infarction: effects of variation in fibrinogen genes and environmental factors.
Journal of thrombosis and haemostasis : JTH - 1 Apr 2007
Mannila M N, Lovely R S, Kazmierczak S C, Eriksson P, Samnegård A, Farrell D H, Hamsten A, Silveira A
Abstract excerpt
BACKGROUND: Fibrinogen gamma', a fibrinogen gamma-chain variant generated via alternative mRNA processing, has been associated with susceptibility to thrombotic disease. OBJECTIVE: The present case-control study searched for potential determinants of the plasma fibrinogen gamma' concentration and examined the relationship between this variant and risk of myocardial infarction (MI). PATIENTS AND METHODS: The...
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