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Article

Indications that paraoxonase-1 contributes to plasma high density lipoprotein levels in familial hypercholesterolemia.

Journal of lipid research - 1 Mar 2005

van Himbergen Thomas M, Roest Mark, de Graaf Jacqueline, Jansen Eugène H J M, Hattori Hiroaki, Kastelein John J P, Voorbij Hieronymus A M, Stalenhoef Anton F H, van Tits Lambertus J H

Abstract excerpt

HDL-associated paraoxonase type 1 (PON1) can protect LDL and HDL against oxidative modification in vitro and therefore may protect against cardiovascular disease. We investigated the effects of PON1 levels, activity, and genetic variation on high density lipoprotein-cholesterol (HDL-C) levels, circulating oxidized LDL (OxLDL), subclinical inflammation [high-sensitive C-reactive protein (Hs-CRP)], and carotid...

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Share to Aryldialkylphosphatase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15576850
DOI: 10.1194/jlr.M400052-JLR200

Genes

PON1
CRP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Indications that paraoxonase-1 contributes to plasma high density lipoprotein levels in familial hypercholesterolemia.PMID 15576850Read ↗

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