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Article

The Molecular Bases of Anti-oxidative and Anti-inflammatory Properties of Paraoxonase 1

2024-10-14

Abstract excerpt

Anti-oxidative and anti-inflammatory properties of high-density lipoprotein (HDL) are thought to be mediated by paraoxonase 1 (PON1), a calcium-dependent hydrolytic enzyme carried on a subfraction of HDL that also carries other anti-oxidative and anti-inflammatory proteins. In humans and mice, low PON1 activity is associated with elevated oxidized lipids, homocysteine (Hcy)-thiolactone, and proteins modified by th...

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Literature Corpus work
5384d857-6e21-5551-860e-a6375f1aab23
DOI
10.20944/preprints202410.0996.v1
Open publication

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The Molecular Bases of Anti-oxidative and Anti-inflammatory Properties of Paraoxonase 1DOI 10.20944/preprints202410.0996.v1
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