Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Relationship of human paraoxonase-1 serum activity and genotype with atherosclerosis in individuals from the Deep South.

Pharmacogenetics and genomics - 1 Dec 2011

Coombes R Hunter, Crow J Allen, Dail MaryBeth, Chambers Howard W, Wills Robert W, Chambers Janice E

Abstract excerpt

OBJECTIVE: Paraoxonase-1 (PON1) is synthesized in the liver and is bound to high-density lipoprotein particles in blood. PON1 protects against the development of atherosclerosis by metabolizing proatherogenic-oxidized lipids. The Southeastern USA (excluding Florida) has the country's highest age-adjusted mortality rate of cardiovascular disease. This study determines the association of PON1 status with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alabama
Share to Aryldialkylphosphatase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Atherosclerosis

Share to Black or African American

Share to PON1 gene

Share to Genotype

Share to Hypertension

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 21960140
DOI: 10.1097/FPC.0b013e32834cebc6
PMCID: PMC4817270

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Relationship of human paraoxonase-1 serum activity and genotype with atherosclerosis in individuals from the Deep South.PMID 21960140Read ↗

Racial differences in paraoxonase-1 (PON1): a factor in the health of southerners?Semantic proximity Read ↗

Paraoxonase 1 polymorphisms within a Mississippi USA population as possible biomarkers of enzyme activities associated with disease susceptibility.Semantic proximity Read ↗

Indications that paraoxonase-1 contributes to plasma high density lipoprotein levels in familial hypercholesterolemia.Semantic proximity Read ↗

Genetic and environmental determinants of the PON-1 phenotype.Semantic proximity Read ↗

Clinical and genetic association of serum paraoxonase and arylesterase activities with cardiovascular risk.Semantic proximity Read ↗

Paraoxonase (PON)-1: a brief overview on genetics, structure, polymorphisms and clinical relevance.Semantic proximity Read ↗

The Molecular Bases of Anti-oxidative and Anti-inflammatory Properties of Paraoxonase 1Semantic proximity Read ↗

Paraoxonase 1 activity, concentration and genotype in cardiovascular diseaseSemantic proximity Read ↗

Factors associated with paraoxonase genotypes and activity in a diverse, young, healthy population: the Coronary Artery Risk Development in Young Adults (CARDIA) study.Semantic proximity Read ↗

Vitamin C and E intake is associated with increased paraoxonase activity.Semantic proximity Read ↗

Determinants of paraoxonase activity in healthy adults.Semantic proximity Read ↗

Pharmacological Interactions of Paraoxonase 1 (PON1): A HDL-Bound Antiatherogenic Enzyme.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.