Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Disruption of C/EBPalpha function in acute myeloid leukemia.

The New England journal of medicine - 2 Dec 2004

Fröhling Stefan, Döhner Hartmut

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CCAAT-Enhancer-Binding Protein-alpha
Share to Leukemia, Myeloid, Acute
Share to Mutation
Share to Prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Transcription Factors

Source

Identifiers

PMID: 15575052
DOI: 10.1056/NEJMp048241

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Disruption of C/EBPalpha function in acute myeloid leukemia.PMID 15575052Read ↗

C/EBPalpha mutations in acute myeloid leukaemias.Semantic proximity Read ↗

Multiple ways of C/EBPalpha inhibition in myeloid leukaemia.Semantic proximity Read ↗

Dysregulation of the C/EBPalpha differentiation pathway in human cancer.Semantic proximity Read ↗

Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells.Semantic proximity Read ↗

Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia.Semantic proximity Read ↗

A dominant-negative mutant of C/EBPalpha, associated with acute myeloid leukemias, inhibits differentiation of myeloid and erythroid progenitors of man but not mouse.Semantic proximity Read ↗

Restoration of C/EBPalpha expression in a BCR-ABL+ cell line induces terminal granulocytic differentiation.Semantic proximity Read ↗

Internal tandem duplication mutation of FLT3 blocks myeloid differentiation through suppression of C/EBPalpha expression.Semantic proximity Read ↗

C/EBPα deregulation as a paradigm for leukemogenesis.Semantic proximity Read ↗

CCAAT/Enhancer binding proteins repress the leukemic phenotype of acute myeloid leukemia.Semantic proximity Read ↗

E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo.Semantic proximity Read ↗

C/EBPα dysregulation in AML and ALL.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.