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Article

CCAAT/Enhancer binding proteins repress the leukemic phenotype of acute myeloid leukemia.

Blood - 1 Feb 2003

Truong Bao-Tran H, Lee Young-Jin, Lodie Tracey A, Park Dorothy J, Perrotti Danilo, Watanabe Naohide, Koeffler H Phillip, Nakajima Hideaki, Tenen Daniel G, Kogan Scott C

Abstract excerpt

CCAAT/enhancer binding proteins (C/EBPs) are a family of factors that regulate cell growth and differentiation. These factors, particularly C/EBPalpha and C/EBPepsilon, have important roles in normal myelopoiesis. In addition, loss of C/EBP activity appears to have a role in the pathogenesis of myeloid disorders including acute myeloid leukemia (AML). Acute promyelocytic leukemia (APL) is a subtype of AML in...

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Source

Identifiers

PMID: 12393450
DOI: 10.1182/blood-2002-05-1374

Genes

PML
EBP
RARA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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