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Article

Mutation of beta-catenin does not coexist with K-ras mutation in colorectal tumorigenesis.

Digestive diseases and sciences - 1 Oct 2004

Shitoh Kazuhisa, Koinuma Koji, Furukawa Taiji, Okada Masaki, Nagai Hideo

Abstract excerpt

Alterations of the APC, K-ras, and beta-catenin genes are defined as early events in colorectal tumorigenesis. These alterations are well-known as constitutents of Vogelstein's pathway, however, the relationship among them is unclear. For understanding colorectal tumorigenesis it is important to evaluate their relationship. We analyzed the relationship between beta-catenin and K-ras gene mutations in clinical...

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Source

Identifiers

PMID: 15573917
DOI: 10.1023/b:ddas.0000043376.41820.a6

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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