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Article

Mutational activation of the RAS-RAF-MAPK and the Wnt pathway in small intestinal adenocarcinomas.

Scandinavian journal of gastroenterology - 1 Aug 2004

Bläker H, Helmchen B, Bönisch A, Aulmann S, Penzel R, Otto H F, Rieker R J

Abstract excerpt

BACKGROUND: Adenocarcinomas of the small and the large intestine share risk factors and morphological features but both tumor types seem to follow different genetic pathways. The aim of this study on small intestinal carcinomas was to analyze alternative mechanisms of activation of pathways that are typically affected in colorectal cancer. METHODS: Twenty-one sporadic carcinomas were investigated for mutations in...

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Source

Identifiers

PMID: 15513360
DOI: 10.1080/00365520410005847

Genes

APC
CTNNB1
KRAS
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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