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Article

[Prediction and identification of autoepitopes of PDC-E2 specific CD8+ CTL in primary biliary cirrhosis patients].

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae - 1 Oct 2004

Liu Hai-ying, Yao Ding-kang, Tu Xiao-qing, Zhou Ye, Zhu Ye, Chen Yan, Fan Lie-ying, Zhong Ren-qian

Abstract excerpt

OBJECTIVE: To identify autoepitopes of E2 subunit of pyruvate dehydrogenase complex (PDC-E2) specific CD8+ CTL in primary biliary cirrhosis (PBC) patients. METHODS: An online database SYFPEITHI was applied to predict HLA-A*0201 restricted epitopes which located in PDC-E2 30-50 aa and 150-190 aa where B-cell epitopes clustered with CD4+ T-cell epitopes. T2 cell line reconstitution and stabilization assay,...

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Share to Antibody-Producing Cells
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epitope Mapping

Share to Epitopes, T-Lymphocyte

Share to HLA-A2 Antigen

Share to Liver Cirrhosis, Biliary

Share to Pyruvate Dehydrogenase Complex

Share to T-Lymphocytes, Cytotoxic

Source

Identifiers

PMID: 15562760

Genes

PDC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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