Article
Probing the Effects of Multisite Mutations in the Lipoic Acid Region of the BCOADC-E2 Protein.
International journal of molecular sciences - 21 Dec 2024
Wang Jinjun, Yang Mingliang, Wei Huixian, Miao Wang, Li Shiyu, Gao Xinru
Abstract excerpt
Primary biliary cholangitis (PBC) is a chronic disease, the prevalence of which has been increasing in recent years. And the prevalence of patients who test negative with existing diagnostic techniques remains high. It was found that the antigenic BCOADC-E2 protein could detect patients with a negative original test. And experiments revealed that the lipoyl domain of BCOADC-E2 plays an important role. The present...
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