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Article

Etiopathogenesis of primary biliary cirrhosis.

World journal of gastroenterology - 7 Jun 2008

Lleo Ana, Invernizzi Pietro, Mackay Ian-R, Prince Harry, Zhong Ren-Qian, Gershwin M-Eric

Abstract excerpt

Primary biliary cirrhosis (PBC) is an autoimmune disease of the liver characterized by progressive bile duct destruction eventually leading to cirrhosis and liver failure. The serological hallmark of the disease is the presence of circulating antimitochondrial antibodies (AMA). These reflect the presence of autoreactive T and B cells to the culprit antigens, the E2 subunits of mitochondrial 2-oxo-acid...

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Share to Liver Cirrhosis, Biliary
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Bile Ducts, Intrahepatic

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Source

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Identifiers

PMID: 18528930
DOI: 10.3748/wjg.14.3328
PMCID: PMC2716587

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PDC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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