Autoreactive liver-infiltrating T cells in primary biliary cirrhosis recognize inner mitochondrial epitopes and the pyruvate dehydrogenase complex.

doi:10.1016/s0168-8278(05)80276-4

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Article

Autoreactive liver-infiltrating T cells in primary biliary cirrhosis recognize inner mitochondrial epitopes and the pyruvate dehydrogenase complex.

Journal of hepatology - 1 Jul 1993

Löhr H, Fleischer B, Gerken G, Yeaman S J, Meyer zum Büschenfelde K H, Manns M

Abstract excerpt

Primary biliary cirrhosis (PBC) is characterized by lymphoid infiltrates in the portal tracts of the liver and the occurrence of antimitochondrial autoantibodies in serum directed against components of the pyruvate dehydrogenase complex and the other alpha-keto acid dehydrogenase complexes. These...

Topics

Adolescent
Adult
Aged
Antibodies, Monoclonal
Autoantibodies
Cell Movement
Cells, Cultured
Enzyme-Linked Immunosorbent Assay
Epitopes
Female
Humans
Liver
Liver Cirrhosis, Biliary
Male
Middle Aged
Mitochondria, Liver
Phenotype
Pyruvate Dehydrogenase Complex

Source

Open in PubMed

Identifiers

PMID: 7693799
DOI: 10.1016/s0168-8278(05)80276-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7693799-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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