Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The proto-oncogene Fgr regulates cell migration and this requires its plasma membrane localization.

Experimental cell research - 15 Jan 2005

Continolo Silvia, Baruzzi Anna, Majeed Meytham, Caveggion Elena, Fumagalli Laura, Lowell Clifford A, Berton Giorgio

Abstract excerpt

Fgr participates in integrin signaling in myeloid leukocytes. To examine the role of its specific domains in regulating cell migration, we expressed various Fgr molecules in COS-7 cells. Full-length, membrane-bound Fgr, but not an N-terminal truncation mutant that distributed to an intracellular compartment, increased cell migration on fibronectin and enhanced phosphorylation of the p85 subunit of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fibronectins
Share to Focal Adhesion Kinase 1

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Focal Adhesion Protein-Tyrosine Kinases

Share to Microfilament Proteins

Share to Precipitin Tests

Share to rac GTP-Binding Proteins

Share to rho GTP-Binding Proteins

Share to src-Family Kinases

Source

Identifiers

PMID: 15561106
DOI: 10.1016/j.yexcr.2004.09.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The proto-oncogene Fgr regulates cell migration and this requires its plasma membrane localization.PMID 15561106Read ↗

The Src family kinase Fgr is a transforming oncoprotein that functions independently of SH3-SH2 domain regulationSemantic proximity Read ↗

RSK2 drives cell motility by serine phosphorylation of LARG and activation of Rho GTPases.Semantic proximity Read ↗

Radil controls neutrophil adhesion and motility through β2-integrin activation.Semantic proximity Read ↗

Phosphorylation of GMFγ by c-Abl coordinates lamellipodial and focal adhesion dynamicsSemantic proximity Read ↗

R-Ras and Rac GTPase cross-talk regulates hematopoietic progenitor cell migration, homing, and mobilization.Semantic proximity Read ↗

The Viral G Protein-Coupled Receptor ORF74 Hijacks β-Arrestins for Endocytic Trafficking in Response to Human ChemokinesSemantic proximity Read ↗

Parallel CRISPR screens reveal pathways controlling the cell surface levels of the attractant receptor FPR1Semantic proximity Read ↗

Constitutive activation of oncogenic PDGFRα-mutant proteins occurring in GIST patients induces receptor mislocalisation and alters PDGFRα signalling characteristics.Semantic proximity Read ↗

Regulation of cell motility by tyrosine phosphorylated villin.Semantic proximity Read ↗

The tyrosine kinase pyk2 promotes migration and invasion of glioma cells.Semantic proximity Read ↗

Rgnef (p190RhoGEF) knockout inhibits RhoA activity, focal adhesion establishment, and cell motility downstream of integrins.Semantic proximity Read ↗

β3 integrin-EGF receptor cross-talk activates p190RhoGAP in mouse mammary gland epithelial cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.