Article

Phosphorylation of GMFγ by c-Abl coordinates lamellipodial and focal adhesion dynamics

2018-01-16

Abstract excerpt

During cell migration a critical interdependence between protrusion and focal adhesion dynamics is established and tightly regulated through signaling cascades. Here we demonstrate that c-Abl, a non-receptor tyrosine kinase, can control these migratory structures through the regulation of two actin-associated proteins, glia maturation factor- γ (GMF γ ) and Neural Wiskott-Aldrich syndrome protein (N-WASP). Pho...

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Literature Corpus work: a804e024-d2ac-5a6a-ae79-a79f6b6c15e2
DOI: 10.1101/248914

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