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Article

Novel exonic mu-opioid receptor gene (OPRM1) polymorphisms not associated with opioid dependence.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Feb 2005

Smith Rachel J, Doyle Glenn A, Han Angela M, Crowley James J, Oslin David W, Patkar Ashwin A, Mannelli Paolo, Demaria Peter A, O'brien Charles P, Berrettini Wade H

Abstract excerpt

The mu-opioid receptor (MOR) mediates reward and dependence associated with opioids and other commonly abused substances. Variability in the MOR gene, OPRM1, may influence risk for opioid dependence. In this study, associations between two single nucleotide polymorphisms (SNPs), dbSNP rs540825 and dbSNP rs562859, and opioid dependence were investigated. The two SNPs are located in the protein coding region of the...

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Source

Identifiers

PMID: 15558714
DOI: 10.1002/ajmg.b.30105

Genes

OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Novel exonic mu-opioid receptor gene (OPRM1) polymorphisms not associated with opioid dependence.PMID 15558714Read ↗

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