Article
Identification and characterization of six new alternatively spliced variants of the human mu opioid receptor gene, Oprm.
Neuroscience - 1 Jan 2005
Pan L, Xu J, Yu R, Xu M-M, Pan Y-X, Pasternak G W
Abstract excerpt
The mu opioid receptor plays an important role in mediating the actions of morphine and morphine-like drugs. Receptor binding and a wide range of pharmacological studies have proposed several mu receptor subtypes, but only one mu opioid receptor (Oprm) gene has been isolated. Like the mouse and rat, the human Oprm gene undergoes alternative splicing. In the present studies, we have identified and characterized...
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