Article
Mu opioid receptor gene variants: lack of association with alcohol dependence.
Molecular psychiatry - 1 Jan 2000
Bergen A W, Kokoszka J, Peterson R, Long J C, Virkkunen M, Linnoila M, Goldman D
Abstract excerpt
The mu opioid receptor is implicated in the reward, tolerance and withdrawal effects of alcohol and other drugs of abuse. This hypothesis is supported by the effects of alcohol on beta-endorphin release, of mu opioid receptor agonists and antagonists on alcohol consumption, and by the activation...
Topics
- Adult
- Alcoholism
- Animals
- Asian People
- Chromosome Mapping
- Exons
- Female
- Finland
- Genetic Linkage
- Genetic Variation
- Genotype
- Haplotypes
- Humans
- Indians, North American
- Male
- Mice
- Mice, Inbred Strains
- Nuclear Family