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Article

Activated Ras induces lens epithelial cell hyperplasia but not premature differentiation.

The International journal of developmental biology - 1 Jan 2004

Reneker Lixing W, Xie Leike, Xu Li, Govindarajan Venkatesh, Overbeek Paul A

Abstract excerpt

Growth factor signaling is implicated in the regulation of lens cell proliferation and differentiation during development. Activation of growth factor receptor tyrosine kinases is known to activate Ras proteins, small GTP-binding proteins that function as part of the signal transduction machinery. In the present study, we examined which classical Ras genes are expressed in lens cells during normal development and...

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PMID: 15558479
DOI: 10.1387/ijdb.041889lr

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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